Hirotsugu Suwanai

Publications（Selected by Year）

2025

Arakawa N, Aoyama T, Suwanai H, Toda G, Takamoto I, Okazaki Y, et al. Elucidation of the clinical traits of diabetic chorea through a questionnaire survey of people with diabetic chorea from 59 Japanese hospitals. J Diabetes Investig. 2025;16(4):680-8.

Shikuma J, Nagai Y, Otaki M, Shimizu N, Wada Y, Sasaki-Shima J, et al. Anterior-Posterior Abdominal Diameter and Waist Circumference Have Comparable Predictive Ability for Visceral Fat Area. Obes Sci Pract. 2025;11(1):e70047.

Suwanai H, Kanda M, Harada K, Ishii K, Iwasaki H, Hara N, et al. Diabetes with COVID-19 was a significant risk factor for mortality, mechanical ventilation, and renal replacement therapies: A multicenter retrospective study in Japan. PLoS One. 2025;20(3):e0319801.

2024

Iwasaki H, Suwanai H, Yakou F, Sakai H, Ishii K, Hara N, et al. Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity. Thyroid. 2024;34(5):659-67.

Sasako T, Suzuki K, Odawara S, Suwanai H, Akuta N, Kubota N, et al. Corticosteroid-triggered acute skeletal muscle loss in lipodystrophy: A case report. J Diabetes Investig. 15. Japan: © 2024 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.; 2024. p. 782-5.

Sugai K, Sasaki J, Wada Y, Shimizu N, Ishikawa T, Yanagi K, et al. Predictive patterns of lower urinary tract symptoms and bacteriuria in adults with type 2 diabetes. Diabetol Int. 2024;15(2):253-61.

2023

Hara N, Suwanai H, Yakou F, Ishii K, Iwasaki H, Abe H, et al. Clinical characteristics and human leukocyte antigens in patients with immune checkpoint inhibitor-induced type 1 diabetes and pituitary dysfunction: a single center prospective study. Endocrine. 2023.

2022

Hara N, Suwanai H, Abe H, Yakou F, Ishikawa T, Urayama M, et al. Hypercalcemia associated with dysgerminoma and elevation of calcitriol: A case report and review of the literature. SAGE Open Med Case Rep. 10: © The Author(s) 2022.; 2022. p. 2050313×211068562.

Iwasaki H, Suwanai H, Sakai H, Ishii K, Hara N, Satomi K, et al. Ventricular fibrillation immediately after the treatment of Graves’ disease coexisting with atypical angina and long QT syndrome: a case report. Thyroid Res. 2022;15(1):18.

Sakurai M, Sasaki J, Suwanai H, Shikuma J, Ito R, Odawara M, et al. A cross-sectional study of the correlation between diabetic therapy and serum zinc concentrations. Diabetol Int. 2022;13(1):177-87.

Shikuma J, Sakakura K, Sugiyama-Takahashi M, Nakamura Y, Nagai Y, Suwanai H, et al. Hematocrit elevation after SGLT2 inhibitor administration may be associated with the degree of proximal tubular damage. Medicine (Baltimore). 2022;101(42):e31122.

Tamaru S, Suwanai H, Abe H, Sasaki J, Ishii K, Iwasaki H, et al. Machine learning approach to predict subtypes of primary aldosteronism is helpful to estimate indication of adrenal vein sampling. High Blood Press Cardiovasc Prev. 2022.

2021

Abe H, Suwanai H, Kambara N, Sano K, Shikuma J, Akaoka H, et al. A Rare Case of Ectopic Adrenocorticotropic Hormone Syndrome with Recurrent Olfactory Neuroblastoma. Intern Med. 2021;60(1):105-9.

Ikushima YM, Awazawa M, Kobayashi N, Osonoi S, Takemiya S, Kobayashi H, et al. MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis. Diabetes. 2021;70(7):1519-35.

Ishii K, Suwanai H, Saito T, Motohashi N, Hirayama M, Kondo A, et al. A case of diabetic ketoacidosis in a patient with COVID-19 and newly diagnosed type 1 diabetes. Clin Case Rep. 9: © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.; 2021. p. e04881.

Ishikawa T, Sakai H, Itaya T, Hirotsugu S, Shikuma J, Miwa T, et al. Falsely diagnosed thyrotoxicosis caused by anti-streptavidin antibodies and pre-wash procedures. Thyroid Res. 2021;14(1):17.

Suwanai H, Watanabe R, Matsumura H. Reply: Dipeptidyl Peptidase-4 Inhibitor Reduces the Risk of Developing Hypertrophic Scars and Keloids following Median Sternotomy in Diabetic Patients: A Nationwide Retrospective Cohort Study Using the National Database of Health Insurance Claims of Japan. Plast Reconstr Surg. 147. United States 2021. p. 1068e-9e.

2020

Asakage M, Usui Y, Nezu N, Shimizu H, Tsubota K, Umazume K, et al. Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing. J Clin Med. 2020;9(11).

Cui G, Shimba A, Ma G, Takahara K, Tani-Ichi S, Zhu Y, et al. IL-7R-Dependent Phosphatidylinositol 3-Kinase Competes with the STAT5 Signal to Modulate T Cell Development and Homeostasis. J Immunol. 2020;204(4):844-57.

Hirota Y, Suwanai H, Yamauchi T, Kadowaki T. Clinical Features of Type B Insulin Resistance in Japanese Patients: Case Report and Survey-Based Case Series Study. J Diabetes Res. 2020;2020:4359787.

Ishikawa T, Suwanai H, Shikuma J, Suzuki R, Yamanaka T, Odawara M, et al. Protein kinase C promotes choline transporter-like protein 1 function via improved cell surface expression in immortalized human hepatic cells. Mol Med Rep. 2020;21(2):777-85.

Suwanai H, Watanabe R, Sato M, Odawara M, Matsumura H. Dipeptidyl Peptidase-4 Inhibitor Reduces the Risk of Developing Hypertrophic Scars and Keloids following Median Sternotomy in Diabetic Patients: A Nationwide Retrospective Cohort Study Using the National Database of Health Insurance Claims of Japan. Plast Reconstr Surg. 2020;146(1):83-9.

Toda G, Soeda K, Okazaki Y, Kobayashi N, Masuda Y, Arakawa N, et al. Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation. Mol Cell. 2020;79(1):43-53.e4.

Yakou F, Suwanai H, Ishikawa T, Itou M, Shikuma J, Miwa T, et al. A Novel Homozygous Mutation of Thyroid Peroxidase Gene Abolishes a Disulfide Bond Leading to Congenital Hypothyroidism. Int J Endocrinol. 2020;2020:9132372.

2019

Abe H, Shikuma J, Suwanai H, Sano K, Okumura T, Kan K, et al. Assessing hypoglycemia frequency using flash glucose monitoring in older Japanese patients with type 2 diabetes receiving oral hypoglycemic agents. Geriatr Gerontol Int. 2019;19(10):1030-5.

2010

Suwanai H, Wilcox MA, Mathis D, Benoist C. A defective Il15 allele underlies the deficiency in natural killer cell activity in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2010;107(20):9305-10.

2002

Suwanai H, Matsushita H, Kobayashi H, Ikeda Y, Kizaki M. A novel therapeutic technology of specific RNA inhibition for acute promyelocytic leukemia: improved design of maxizymes against PML/RARalpha mRNA. Int J Oncol. 2002;20(1):127-30.

Ayuko Suwanai

Publications

Hayashi M, Narumi S, Sato T, Amano N, Suwanai AS, Haruna H, et al. Genetic and Clinical Characteristics of 185 Japanese Children with 46,XY Differences of Sex Development. J Clin Endocrinol Metab. 2024.

Abe K, Narumi S, Suwanai AS, Adachi M, Muroya K, Asakura Y, et al. Association between monoallelic TSHR mutations and congenital hypothyroidism: a statistical approach. Eur J Endocrinol. 2018;178(2):137-44.

Nishina-Uchida N, Fukuzawa R, Numakura C, Suwanai AS, Hasegawa T, Hasegawa Y. Characteristic testicular histology is useful for the identification of NR5A1 gene mutations in prepubertal 46,XY patients. Horm Res Paediatr. 2013;80(2):119-28.

Suwanai AS, Ishii T, Haruna H, Yamataka A, Narumi S, Fukuzawa R, et al. A report of two novel NR5A1 mutation families: possible clinical phenotype of psychiatric symptoms of anxiety and/or depression. Clin Endocrinol (Oxf). 2013;78(6):957-65.

Abe K, Narumi S, Suwanai AS, Hamajima T, Hasegawa T. Pseudodominant inheritance in a family with nonautoimmune hypothyroidism due to biallelic DUOX2 mutations. Clin Endocrinol (Oxf). 2015;83(3):394-8.

Ishii T, Hayashi M, Suwanai A, Amano N, Hasegawa T. The effect of intramuscular testosterone enanthate treatment on stretched penile length in prepubertal boys with hypospadias. Urology. 2010;76(1):97-100.